First-line picks and clinical guidance for the presentations under this topic.
Major Depressive Disorder
Persistent low mood, anhedonia, and behavioral withdrawal; thinking turns rigid and self-critical.
Depression responds to multiple evidence-based therapies. Choice depends on severity, recurrence history, interpersonal context, and client preference. For 3+ prior episodes, relapse prevention (MBCT, maintenance IPT) becomes central. Severe presentations usually benefit from combined therapy + medication.
First-line:CBT · IPT · MBCT
Bipolar Disorder
Recurrent depressive and (hypo)manic episodes; mood stabilization is medication-led with adjunctive therapy.
Bipolar disorder is primarily medication-managed (mood stabilizers, atypical antipsychotics). Psychotherapy is adjunctive — psychoeducation, prodrome monitoring, and circadian/sleep regulation reduce relapse.
First-line:CBT · IPT
Perinatal Mood & Anxiety Disorders
Depression, anxiety, OCD, or PTSD during pregnancy or the postpartum year.
PMADs are common (~15–20% of birthing parents) and highly treatable. Screen with EPDS at multiple time points. Untreated perinatal depression has measurable effects on infant attachment and development — treat actively.
First-line:CBT · IPT
Grief & Bereavement
Acute and prolonged grief responses to loss; normal in nearly all cases, occasionally complicated.
Most grief is non-pathological and does not require treatment. When grief becomes prolonged (>12 months, impairing), targeted therapies help. Differentiate from depression — overlap exists but the focus differs.
First-line:IPT · CBT