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Topic hub

Depression therapy

What's first-line, what to pick when, and what to send home.

CBT, IPT, MBCT, ACT, and CFT for the depressed client — with the formulations that distinguish acute episodes from chronic, characterological, perinatal, and geriatric presentations.

6 modalities4 disorders8 worksheets4 cases2 populations1 client explainers

Modalities

The therapies most relevant to this topic.

Disorders

First-line picks and clinical guidance for the presentations under this topic.

Major Depressive Disorder

Persistent low mood, anhedonia, and behavioral withdrawal; thinking turns rigid and self-critical.

Depression responds to multiple evidence-based therapies. Choice depends on severity, recurrence history, interpersonal context, and client preference. For 3+ prior episodes, relapse prevention (MBCT, maintenance IPT) becomes central. Severe presentations usually benefit from combined therapy + medication.

First-line:CBT · IPT · MBCT

Bipolar Disorder

Recurrent depressive and (hypo)manic episodes; mood stabilization is medication-led with adjunctive therapy.

Bipolar disorder is primarily medication-managed (mood stabilizers, atypical antipsychotics). Psychotherapy is adjunctive — psychoeducation, prodrome monitoring, and circadian/sleep regulation reduce relapse.

First-line:CBT · IPT

Perinatal Mood & Anxiety Disorders

Depression, anxiety, OCD, or PTSD during pregnancy or the postpartum year.

PMADs are common (~15–20% of birthing parents) and highly treatable. Screen with EPDS at multiple time points. Untreated perinatal depression has measurable effects on infant attachment and development — treat actively.

First-line:CBT · IPT

Grief & Bereavement

Acute and prolonged grief responses to loss; normal in nearly all cases, occasionally complicated.

Most grief is non-pathological and does not require treatment. When grief becomes prolonged (>12 months, impairing), targeted therapies help. Differentiate from depression — overlap exists but the focus differs.

First-line:IPT · CBT

Worksheets

Free, printable, Quick-Send to clients.

For clients

Plain-language explainers you can share or open together in session.

Worked cases

Anonymized vignettes with formulation across 2–3 modalities.

Populations

What changes when you sit with this population.